We found no significant correlations between circulating Treg cell numbers, identified by CD4+CD25+FoxP3high, CD4+CD45RA+FoxP3low, and CD4+FoxP3+Helios+ assessments and carotid IMT in SLE women with low disease activity and at low risk of CV events. This evidence concerns the gene FOXP3 and systemic lupus erythematosus.