Furthermore, we observed that both the mRNA and protein levels of a collection of NF‐κB downstream effectors that are central co‐ordinators of cancer cell metastasis, such as ICAM1, VCAM1 and MMP9, were decreased by RPS15A knockdown, but increased by RPS15A overexpression (Figure 5E,F). This evidence concerns the gene NFKB1 and cancer.