TRIM28 and acute promyelocytic leukemia: We documented that LMP1 induces the sumoylation of interferon regulatory factor-7 (IRF7) and KRAB-associated protein-1 (KAP1)7,9, and LMP1 is known to induce the formation of promyelocytic leukemia nuclear bodies62,63, which is tightly regulated by protein sumoylation.