CEBPB and hepatocellular carcinoma: Notably, these HCC driver genes were not only suppressed in C/EBPβ enh−/− cells (P < 0.05; Fig. 6i, j), but also upregulated and correlated with C/ebpβ expression in the pre-malignant liver tissues of the HBx TG HCC model (P < 0.05; Supplementary Fig. 7d, e).