Mcleod et al. utilizing PCa tissue microarrays from 207 patients, established a correlation between the presence of ERG protein expression by immunohistochemistry (IHC) and ERG rearrangement by using fluorescence in situ hybridization (FISH) with a sensitivity and specificity of 95.7% and 96.5% respectively [11]. Here, ERG is linked to posterior cortical atrophy.