PAGE4 and posterior cortical atrophy: Accumulating evidence from varied studies including those from our group has shown that PAGE4 is re-expressed in human diseased prostate, particularly in the stroma of symptomatic benign prostatic hyperplasia (BPH) [5], and in the epithelia of proliferative inflammatory atrophy (PIA) that is considered as a precursor of PCa, as well as in PCa itself [6–11].