Consistent with these results, the flow cytometry data revealed that ZDHHC23 was exclusively co-expressed with the proneural GSC marker, CD133, in the leading edge, and ZDHHC18 was tightly associated with the mesenchymal GSC marker, CD44, in the necrotic region of GBM (Fig. 3c). This evidence concerns the gene ZDHHC18 and glioblastoma.