In ductal carcinoma samples, significant inverse correlations were observed between tumor levels of miR-10b and tumor levels of six target mRNAs: SRSF1 (R = − 0.26, p = 0.047), PIEZO1 (R = − 0.26, p = 0.048), MAPRE1 (R = − 0.28, p = 0.033), CDKN2A (R = − 0.29, p = 0.031), TP-53 (R = − 0.371, p = 0.0045) and TRA2B (R = − 0.37, p = 0.009). This evidence concerns the gene PIEZO1 and breast ductal adenocarcinoma.