At the end of VL treatment, she had severe liver injury, presenting hyperbilirubinemia, hypoalbuminemia, and increased liver and canalicular enzymes: alanine transaminase (ALT) 354 IU/mL; aspartate transaminase (AST) 401 IU/mL; alkaline phosphatase 993 mg/dL; γ-glutamyl transferase 1048 mg/dL; total bilirubin 5.77 mg/dL, leading to fecal acholia, jaundice, and hypoalbuminemia (2.7 g/dL). The gene discussed is GPT; the disease is Hyperbilirubinemia.