VDR and type 1 diabetes mellitus: Furthermore, we did not have single nucleotide polymorphisms of the vitamin D pathway in the children, which might have been interesting to have, as some of us, participating in a large international collaboration study, found that 25(OH)D levels and vitamin D receptor polymorphism may have a combined role in the development of islet autoimmunity in children at increased genetic risk for T1D (27).