PBK and lung carcinoma: PDZ‐binding kinase (PBK) is defined as a mitogen‐activated protein kinase between MEK7 and MEK1/2, a mitosis kinase that enhances cytokinesis as well as a kinase that promotes metastasis and cell migration in lung cancer.6 MicroRNA‐216b (miR‐216b) was recently demonstrated to play a repressive role in tumors by regulating the expression of PBK.7 According to the TargetScan database, there are theoretical complementary sequences between 3′‐untranslated region (UTR) of PBK and miR‐372.