Previously, it has been revealed that PBK attenuates DNA damage checkpoint through suppression of p53, thus augmenting tumor cell growth.34 Also, increased PBK promoted the progression of tumor cells by inhibiting p53.35 Hence, it is reasonable to conclude that miR‐372 targets PBK to down‐regulate its expression, thus preventing the development of NPC. Here, TP53 is linked to neoplasm.