WDR76 and urinary bladder cancer: The decreases and increases in oncogenic RAS by overexpression and knockdown of WDR76, respectively, were further confirmed using the three cancer cell lines harboring a RAS mutation (i.e., T24T bladder cancer cell line (HRASG12V), LoVo colon cancer cell line (KRASG13D), and HepG2 hepatocellular carcinoma cell line (NRASQ61L)) (Fig. 2h, i).