We observed statistically significant increases in ZIKV infection in the vagina and uterus and a trend toward greater infection in the cervix at 7 dpi of progesterone only-treated OVX hSTAT2 KI Ifnlr1−/− compared to hSTAT2 KI mice (Fig. 3e–g). The gene discussed is IFNLR1; the disease is Zika virus infectious disease.