We then examined methylation in a shortlist of genes that were previously associated with early life stress and psychiatric disorders as well as placental functioning: Ank3, Avp, Avpr1a, Avpr1b, Bdnf, Cacna1c, Cyp11b1, Cyp11b2, Fkbp5, Hsd11b1, Igf2, Morc1, Nr3c1, Oxt, Oxtr, Pclo, Slc6a4. This evidence concerns the gene PCLO and psychiatric disorder.