HDAC1 and hepatocellular carcinoma: The literature data for the expression of HDAC1 and 8 as well as CARM1 indicating that these genes also have influence on tumorigenesis, EMT and the hepatic function [4,10,27,28] but they are not de-regulated in HepG2 however, we have found a de-regulation in the other tested HCC cell lines, which was another reason for using the cell line HepG2 for the further experiments.