High levels of HOTAIR correlated with metastasis and poor prognosis have been found in lung cancer [174], hepatocellular carcinoma [175,176], breast cancer [166], gastric cancer [177,178], colorectal cancer [179], cervical cancer [180], ovarian cancer [181], head and neck carcinoma [182], and esophageal squamous cell carcinoma [183]. The gene discussed is HOTAIR; the disease is colorectal cancer.