TAL1 on the other hand is detectable in the chronic myelogenous leukaemia (CML) cell line K562 and in hCD34+ donor cells, while it is not expressed in the acute promyelocytic leukaemia cell line HL60 and in the human embryonic kidney cell line HEK293T (Fig 1C). Here, TAL1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.