Moreover, GRP78 expression levels in both renal tumor tissue and tumor-associated perinephric adipose tissue were not associated with grade or size of ccRCC tumors, except for a weak metastatic predictive potential that was found for GRP78 staining intensity in ccRCC tumor-associated perinephric adipose tissue. The gene discussed is HSPA5; the disease is nonpapillary renal cell carcinoma.