In previous studies, up to eleven regions within the major histocompatibility complex (MHC) have been identified to exhibit statistically significant independent effects of association with MS in White, non-Hispanic populations: six HLA-DRB1, one HLA-DPB1, one HLA-A, two HLA-B alleles, and one signal in a region spanning from MICB to LST1[11]. The gene discussed is HLA-DRB1; the disease is myeloid sarcoma.