In four cells lines, including the gliomas U251 and SNB19, the renal cell carcinoma TK10, and the colorectal carcinoma HCC2998, a pattern of positive correlations (Pearson’s r ≥ 0.4) was identified for every pairwise combination of STAT1, VAV2, and YES1 (see Fig 7 for U251). Here, VAV2 is linked to central nervous system cancer.