There was a direct correlation between TGF-β1 and TβRIexpressions in the AD group (Y=0.383X + 0.584; r2=0.335, r=0.579,P=0.007); and there was a significant direct correlationbetween TGF-β1 and TβRI expressions in the CAD group(Y=0.708X + 0.113; r2=0.254, r=0.504, P=0.024) (Figure 3). The gene discussed is TGFBR1; the disease is Alzheimer disease.