Sequencing analyses of both tumors revealed a loss of the wild-type BRCA1 allele by loss of heterozygosity in both the acinic cell carcinoma and the invasive ductal carcinoma in association with two different somatic TP53 mutations, suggesting that acinic cell carcinoma develops independent from invasive ductal carcinoma. Here, TP53 is linked to invasive ductal breast carcinoma.