CD274 and neoplasm: Given this strong overlap, it was not surprising that both high tumour and stromal derived PD-L1 were significantly associated with improved RFS (Tumour HR 0.455 (95%CI 0.274-0.909) p=0.0237, Stroma HR 0.421 (95%CI 0.26-0.872) p=0.0164) (Figure 4(d)) with similar though nonsignificant trends for OS (Supp Fig2B).