Moreover, Wattad and colleagues showed that patients with FLT3-ITD-mutated AML on salvage therapy had a high risk of relapse even after a potentially curative allogeneic hematopoietic stem cell transplant (alloHSCT), with the FLT3-ITD allelic ratio correlating directly with survival [50]—an observation that underscores patients’ poor prognosis in this setting. This evidence concerns the gene FLT3 and acute myeloid leukemia.