Using MR image analysis at day 28, brain tumor size was quantified and it was found that brain tumors present in mice injected with PAK1 knockdown cells were significantly smaller (0.05 ± 0.01 mm3) than control tumors (0.10 ± 0.02 mm3) (p = 0.015) (Fig. 8g). Here, PAK1 is linked to brain neoplasm.