This led us to KIAA0528 for multiple reasons: (1) it was identified as the top binding protein41, (2) this interaction was validated with anti-KIAA and anti-CDK5 immunoprecipitations (IPs)41, and (3) KIAA0528 is involved in GLUT4 transport42, a motor-dependent process relevant in diabetes. Here, CDK5 is linked to diabetes mellitus.