SERPINF1 and retinal degeneration: Administration of PEDF in models of retinal degeneration, such as rd1 and rds mice or RCS rats (Cayouette et al., 1999; Comitato et al., 2018; Miyazaki et al., 2003; Wang et al., 2013), or in models of light-induced retinal damage (Cao et al., 2001; Imai et al., 2005), can delay photoreceptor degeneration.