DMD and Duchenne muscular dystrophy: In order to eliminate the genetic variability of the individual cell lines from specific effect of NAC, all WT and all DMD hPSC lines were pooled together, showing that significantly elevated ROS level in DMD hPSC (p < 0.0001) can be reduced to the level of WT hPSC by the application of NAC (p = 0.6270 as evaluated by Wilcoxon test comparing control values from WT iPSC and WT hESC to corresponding NAC treated DMD lines, Figure S8, Supplementary Table S2).