Not only is our recommendation consistent with that of Caplin and Edelman [48] and of Legnani et al. [36] in the specific context of thrombophilia screening before initiating COCs, but it also echoes King et al.’s [22] arguments for offering women BRCA1 and BRCA2 screening as part of routine care. The gene discussed is BRCA2; the disease is Rare hereditary thrombophilia.