MIER1 and cancer: For example, the sesquiterpenoid euplotin C or the protein pheromone Er-1 from the Euplotes species, have been previously shown to act respectively as an anti-cancer compound or as an immune-modulatory factor [1,29,30,31,32]; an antibiotic activity against methicillin-resistant Staphylococcus aureus has been recognized in the quinone pigment blepharismin isolated from Blepharisma japonicum [33].