Notably, tau phosphorylation was increased in FTD-MAPT neurons compared with controls (Figure 1A), including at Ser404 and Ser202/Thr205 (AT8), epitopes typically hyperphosphorylated in tau-mediated dementias (Alonso et al., 2004, Wang et al., 2013). The gene discussed is MAPT; the disease is frontotemporal dementia.