YWHAZ and acute promyelocytic leukemia: Most proteins that were higher expressed in APL were involved in the pro‐apoptotic pathway (e.g., BCL2, BCL2L1, DIABLO, YAP1p, YWHAZ) or were linked to a higher proliferation (e.g., CDKN2A, PIK3CA), which may suggest a more pro‐apoptotic tendency of those cells, and that once the differentiation block is abrogated by the ATRA treatment, those cells tend to be more sensitive to the ATO‐induced apoptosis.