These three clusters were primarily formed by altered expression of YAP1 (relatively low in APL) and 14‐3‐3 protein zeta (YWHAZ) (higher in APL compared to AML), and these are both members of the HIPPO and TP53 PFG, again highlighting differences between APL and AML in apoptosis‐regulating pathways. The gene discussed is TP53; the disease is acute promyelocytic leukemia.