2014; Wang et al. 2014; Tsuchida et al. 2017). However, after 5 days, REDD‐2 expression was elevated in rats treated with DEXA without changes in REDD‐1 (Nishida et al. 2015). These results corroborate our results on REDD1/2 expression regarding DEXA administration (without N‐3 supplemented), which showed a REDD1/2 time‐dependent action on glucocorticoid‐induced muscle atrophy. However, when associated to N‐3, REDD‐1 expression remained elevated even after 10 days of DEXA administration, which points to a prolonged state of muscular atrophy. The gene discussed is DDIT4; the disease is muscle atrophy.