Interleukin (IL-32, NK4) is a novel cytokine originally isolated from activated T cells. IL-32 behaves as a multifaceted cytokine involving autoimmune diseases, infections, and neoplasia, inducing inflammation in the tumor environment and quite often blocking viral multiplication while it has a vital role in endothelial functions and angiogenesis. The gene discussed is IL32; the disease is autoimmune disease.