CD4 and HIV infectious disease: •    All adolescents and adults including pregnant women with HIV infection and CD4counts of ≤350 cells/mm3, should start ART,•    First-line therapy should consist of an NNRTI + two NRTIs, one of which should beAZT or TDF•    Second-line ART should consist of a ritonavir-boosted protease inhibitor (PI) plustwo NRTIs, one of which should be AZT or TDF•    Irrespective of CD4 cell counts, patients coinfected with HIV and TB should bestarted on ART•    Irrespective of CD4 cell counts or WHO clinical stage, patients who requiretreatment for HBV infection should start ART.