AKT1 and cutaneous melanoma: In the cutaneous melanomas patients, p-Akt1 showed positive association with ulceration (P < .0001), growth phase (P < .0001), Breslow’s Thickness (P < .0001), mitotic rate (P = .003), Clark’s Level (P < .0001), metastasis (P = .008), AJCC-stage (P < .0001), and recurrence (P < .0001), as shown in Table 4.