The expression levels of 2 of the 3 genes negatively correlated with YBX1 (ESR1 and GATA3) were significantly (P < 0.05) lower in patients who relapsed after their primary surgery than in those who did not relapse (Figure 4C), suggesting that YBX1 and its correlated genes could be used as predictive genes for recurrence and poor outcomes in breast cancer patients. This evidence concerns the gene YBX1 and breast cancer.