We first found that, tumor infiltrating CD4+ T cells show no difference in the expression of the TNFR I (Supplementary Figure 6C) but a downregulation of the TNFR II was detected on CD4+ T cells in the lungs of tumor bearing STAT1 KO mice compared to tumor bearing Bl6/C57j mice (Figure 6D). Here, TNFRSF1A is linked to neoplasm.