LRPAP1 and Insulin resistance: MicroRNAs miR-19a, miR-499, miR-539, miR-363, miR-495, miR-7a, and miR-429, which are reported to be increased in diabetic patients or animal models and/or contribute to insulin resistance, were increased in ZL-Rap hearts suggesting that Rap treatment induces a diabetes-associated miRNA transcriptome in ZL-Rap hearts.