However, the differences of ADP, RBP4, CK18-M30 and CK18-M65 among different genotypes of rs1260326 and rs780094 in NAFLD patients were not statistically significant, which suggested the ADP, RBP4 and CK18-M30 might not be functioned by rs1260326 and rs780094 in the formation of NAFLD, and further fine-mapping studies in the susceptible region of the variants and more NAFLD-related serum cytokines are needed. Here, RBP4 is linked to metabolic dysfunction-associated steatotic liver disease.