This NMA provided 4 direct comparisons (MBP with OAB vs MBP, MBP with OAB vs OAB, MBP vs no preparation, and MBP vs OAB) and 2 indirect comparisons (MBP with OAB vs no preparation and OAB vs no preparation) of MBP and OAB approaches before elective CRS, with the following 8 short-term outcomes evaluated: total SSI, incisional SSI, organ/space SSI, anastomotic leak, mortality, readmissions/reoperations, UTI, and pulmonary complications. This evidence concerns the gene MBP and congenital rubella syndrome.