In pregnant women, the highest proportion of complications (61.1%) corroborates previous dramatic reports on Q fever during pregnancy.27 Placentitis and microthrombi have been described.23 In children, Q fever has been marked by an age-related increase in incidence.28 The imbalance in the sex ratio distribution of the disease occurred after puberty, and males were most affected by vascular infections and presented with a higher secretion of aCL antibodies during acute Q fever. This evidence concerns the gene ACLY and Q fever.