When examined in molecular subtypes, GRPR is over-expressed in 86.2% of luminal-A and 82.8% of luminal-B HER2 negative tumors while triple negative breast cancers and HER2-enriched phenotypes exhibit GRPR over-expression in only 7.8% and 21.3% of cases. This evidence concerns the gene ERBB2 and triple-negative breast carcinoma.