The 16 genes that were most highly D23580-up-regulated (≥4 fold-change, FDR ≤0.001) included a β-glucosidase, STM3775 (SL1344_3740); genes involved in cysteine metabolism, cdsH; oxidation of L-lactate, STM1621 (SL1344_1551); and the transcriptional regulator rcsA. Genes that were D23580-down-regulated during infection of macrophages were involved in the uptake of sialic acid (nanM) and maltose or maltodextrin (malEFK) or the secretion and import of siderophores (iroC and iroD). This evidence concerns the gene GIMAP5 and infection.