The increased nuclear staining of MORC2 was observed in poor differentiation gastric cancer compared to well-moderate differentiation and adjacent normal tissues (Fig. 6a, upper panel), poor differentiation gastric cancer tissues with high levels of MORC2 accounted for ~80% of gastric cancer samples (Fig. 6a, upper panel), which showed the striking correlation with decreased C/EBPα (Fig. 6a, down panel). This evidence concerns the gene CEBPA and gastric cancer.