In this case-control study,some SNPs in PRM1 (c.49 C>T, c.102 G>T and c.230A>C) and PRM2 (rs545828790, rs115686767, rs201933708,rs2070923 and rs1646022) were investigated in 30 idiopathic infertile men with teratozoospermia (case group) incomparison with 35 fertile men (controls). The gene discussed is PRM1; the disease is Abnormal sperm morphology.