TheROC analysis identified plasma UCN1 concentration of46 pg/mL as the best cut-off point to differentiate womenwith endometriosis from those with no lesions, with 76%sensitivity, 88% specificity and an AUC equal to 0.827.However, an optimal cut-off that would distinguish endometriosisfrom other benign pathology (including benignovarian cysts, ovarian teratoma, hydrosalpinx, salpingitis,ectopic pregnancy, uterine leiomyoma and ovarian cancer)was not identified. This evidence concerns the gene UCN and ovarian cancer.