The core–shell nanocomposite UCNPs/MB@ZIF‐8@catalase (UCNPs, upconversion NPs; MB, methylene blue) was developed for NIR/H2O2‐responsive photodynamic therapy against hypoxic tumor cells.90 The synthesis procedure involved a one‐pot assembly of a UCNPs/MB@ZIF‐8 core–shell structure and the subsequent surface functionalization of the shell with catalase. This evidence concerns the gene CAT and neoplasm.