The hypothesis of mitochondrial dysfunction playing a major role in PD pathogenesis has been proposed in several studies.[[qv: 19c,36]] Interestingly, LRRK2 seems to control mitochondrial homeostasis via the dynamin‐like protein DLP1.37 We have confirmed compromised mitochondrial function in LRRK2‐G2019S cells,20, 37, 38 but also broadened its characterization in hNESC‐derived neurons. This evidence concerns the gene LRRK2 and Parkinson disease.