ACE and leukemia: The extract of KP can significantly decrease the levels of NO in LPS-triggered RAW264.7 cells, inhibit the adhesive activity of human monocytic leukemia (THP-1) cells to human umbilical vein endothelial cells (HUVECs), downregulate the expression of cell adhesion molecules (CAMs) and inflammatory cytokines, and decrease the production of angiotensin-converting enzyme (ACE)-mediated Ang-II, leading to amelioration of oxidative stress [49] (Table 1).